Mysterious vaping illness characterized by fat-laden cells in the lung
Investigators have identified a previously unrecognized characteristic of the vaping-related respiratory illness that has been emerging in clusters across the US in recent months. Within these...
View ArticleAlcohol-producing gut bacteria could cause liver damage even in people who...
Non-alcoholic fatty liver disease (NAFLD) is the build-up of fat in the liver due to factors other than alcohol, but its cause remains unknown. Now, researchers have linked NAFLD to gut bacteria that...
View ArticleUnravelling an alternative mechanism of airway mucosal immunity
Researchers have identified two key proteins, ASC and NLRP3, in the maintenance of the innate immune homeostasis in the airway. These proteins do so by a caspase-1-independent mechanism, suggesting...
View ArticleAI system accurately detects key findings in chest X-rays of pneumonia...
From 20 minutes or more to 10 seconds. Researchers from Intermountain Healthcare and Stanford University say 10 seconds is about how quickly a new system they studied that utilizes artificial...
View ArticleCheap, quick test identifies pneumonia patients at risk of respiratory...
Researchers have now identified specific fragments of genetic material that play a role in the development of respiratory failure and sepsis in pneumonia patients. The findings could enable doctors to...
View ArticleLow blood oxygen strongly increases sick children's risk of death
Low blood oxygen is more common in sick children than previously thought, and strongly increases children's risk of death, Australian-led research has found.
View ArticleVaccine reduces likelihood of severe pneumonia
A new study has found severe pneumonia decreases by 35 per cent in children who receive a vaccine against a pneumonia-causing bacteria.
View ArticleRemoving body clock gene protects mice against pneumonia
This is the first time a clock gene has been found to affect resistance to bacterial pneumonia, a fatal disease responsible for 5% of all deaths in the UK each year.
View ArticleExposure to diesel exhaust particles linked to pneumococcal disease...
A new study shows that exposure to diesel exhaust particles (DEPs) can increase an individual's susceptibility to pneumococcal disease.
View ArticlePneumonia recovery reprograms immune cells of the lung
Researchers have determined that after lungs recover from infection, alveolar macrophages (immune cells that live in the lungs and help protect the lungs against infection) are different in multiple...
View ArticleNo benefit found in using broad-spectrum antibiotics as initial pneumonia...
Doctors who use drugs that target antibiotic-resistant bacteria as a first-line defense against pneumonia should probably reconsider this approach, according to a new study of more than 88,000 veterans...
View ArticleChest CT findings in coronavirus disease (COVID-19) pneumonia
New research on the novel coronavirus (COVID-19) is a multi-center study (n=101) of the relationship between chest CT findings and the clinical conditions of COVID-19 pneumonia -- which determined that...
View ArticleInfections still responsible for 1 in 5 childhood deaths in England and...
Infections are still responsible for one in five childhood deaths in England and Wales, with respiratory infections topping the league table of known causes, reveals an analysis of the most up to date...
View ArticleNew CT scoring criteria for timely diagnosis, treatment of coronavirus...
Updated CT scoring criteria that considers lobe involvement, as well as changes in CT findings (i.e., ground-glass opacity, crazy-paving pattern, and consolidation), could quantitatively and accurately...
View ArticleTo prevent antimicrobial resistance, vaccinate the world's kids
Childhood vaccination may be a powerful tool in the fight against antimicrobial resistance in low- and middle-income countries, finds a new analysis. The study found that immunization with two common...
View ArticleOsteoporosis treatment may also protect against pneumonia
A recent study found that nitrogen-containing bisphosphonates (N-BPs) such as alendronate, which are widely used to treat postmenopausal osteoporosis, are linked with lower risks of pneumonia and of...
View ArticleCT of coronavirus disease (COVID-19) versus CT of influenza virus pneumonia
A new article investigating the differences in CT findings between coronavirus disease (COVID-19) pneumonia and influenza virus pneumonia found that most lesions from COVID-19 were located in the...
View ArticleFlu, pneumonia vaccinations tied to lower risk of Alzheimer's dementia
Flu (influenza) and pneumonia vaccinations are associated with reduced risk of Alzheimer's disease, according to new research.
View ArticleVaccines against respiratory infections linked to fewer heart failure deaths
Influenza and pneumonia vaccinations are associated with fewer hospital deaths in patients with heart failure. That's the result of a study in nearly 3 million Americans. One out of five individuals...
View ArticleVaccine proves effective against the most severe type of pneumonia
A pneumococcal vaccine was effective at protecting children in Laos against the most severe type of pneumonia, a new study has found.
View ArticleGenetic analysis system yields new insights into bacterial pneumonia
A team of infectious disease researchers has developed a new method to identify virulence genes in Streptococcus pneumoniae, the leading cause of bacterial pneumonia. Using this technique in a mouse...
View ArticleT-cell abnormalities in severe COVID-19 cases
Researchers performed a genetic analysis of T cells from lung tissue of COVID-19 patients. They found abnormalities that resulted in T cell overreaction that may cause severe pneumonia.
View ArticleNew study explains important cause of fatal influenza
It is largely unknown why influenza infections lead to an increased risk of bacterial pneumonia. Researchers have now described important findings leading to so-called superinfections, which claim many...
View ArticleScientists shed new light on how lung bacteria defend against pneumonia
New insight on how bacteria in the lungs protect against invading pathogens has been published.
View ArticleAn atlas of S. pneumoniae and host gene expression during colonization and...
The bacteria Streptococcus pneumoniae colonizes the nasopharynx and can cause pneumonia. Then, it can spread to the bloodstream and cause organ damage. To understand how this pathogen adapts to...
View ArticleDNA test can quickly identify pneumonia in patients with severe COVID-19,...
Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients.
View ArticleStudy finds genetic clues to pneumonia risk and COVID-19 disparities
Researchers have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences.
View ArticleNew vaccine needed for serious childhood pneumonia
A rise in vaccine-resistant bacteria shows the need for a new vaccine to fight childhood empyema after a spike in hospitalisations, a new study reveals.
View ArticleFive days of antibiotics fine for children with pneumonia: Study
The study, involving 281 Ontario children, found that 85.7% of those who received the short course of antibiotics and 84.1% of those who received the longer course of medication were cured two to three...
View ArticleOne third of patients hospitalized with COVID-19 have lung changes after a year
A new study has shown that most patients discharged from hospital after experiencing severe COVID-19 infection appear to return to full health, although up to a third do still have evidence of effects...
View ArticleHow good is your sense of smell?
In a new study, researchers have found a possible link between poor sense of smell and a higher risk of pneumonia hospitalization.
View ArticleStreptococcus pneumoniae sticks to dying lung cells, worsening secondary...
Researchers have found a further reason for the severity of dual infection by influenza and Streptococcus pneumonia -- a new virulence mechanism for a surface protein on the pneumonia-causing bacteria...
View ArticlePandemic of antibiotic resistance is killing children in Bangladesh,...
Pneumonia is the leading cause of death in children worldwide. A new study identifies an unusual pattern of deadly bacteria with resistance to all standard antibiotic therapy in children with pneumonia...
View ArticleNew potential drug target for pneumonia
Researchers report that a recently discovered inflammatory mediator, interleukin-26, appears to have an important role in pneumonia and contribute to the killing of bacteria.
View ArticleNew study shows environmental and social factors contribute to higher rates...
A new study demonstrates that children who are exposed to a certain type of environmental air pollution are more likely to contract community acquired pneumonia, or CAP, and to be hospitalized for...
View ArticleResearchers target a mouse’s own cells, rather than using antibiotics, to...
Researchers have discovered a therapy that targets host cells rather than bacterial cells in treating bacterial pneumonia in rodents. The method involves white blood cells of the immune system called...
View ArticleElectronic pneumonia decision support helps reduce mortality by 38 percent in...
A real-time electronic decision support system helped clinicians at community hospitals provide best practice care for emergency department patients with pneumonia, resulting in decreased intensive...
View ArticleCOVID-19 pneumonia increases dementia risk
A new study shows patients hospitalized with COVID-19 pneumonia have a higher risk of developing dementia than those with other types of pneumonia.
View ArticleNanoparticle sensor can distinguish between viral and bacterial pneumonia
Many different types of bacteria and viruses can cause pneumonia, but there is no easy way to determine which microbe is causing a particular patient's illness. This uncertainty makes it harder for...
View ArticleGenomics empowers vaccine makers to tackle shapeshifting bacteria
A pioneering genomic surveillance study has provided the clearest picture yet of the arms race between Streptococcus pneumoniae, the bacterium responsible for a range of illnesses such as pneumonia and...
View ArticleTiny swimming robots treat deadly pneumonia in mice
Engineers have developed microscopic robots, called microrobots, that can swim around in the lungs, deliver medication and be used to clear up life-threatening cases of bacterial pneumonia. In mice,...
View ArticleDiscovery of T-cells that protect against deadly pneumococcal disease
A new study reveals how resistance to bacteraemic pneumonia is provided by a unique subset of lung T regulatory cells.
View ArticleFomepizole helps overcome antibiotic-resistant pneumonia in mice, study finds
Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually. A new study suggests that the FDA-approved drug Fomepizole may reduce disease severity in...
View ArticleResearchers uncover new differences in bacteria's sugar coat to aid...
Many disease-causing bacteria like Streptococcus pneumoniae (S. pneumoniae) are encased in a sugar layer called the capsular polysaccharide (CPS). This layer is often essential for infections. In a...
View ArticleNear-universal T cell immunity towards a broad range of bacteria
Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a...
View ArticleHow the respiratory tract microbiome influences the severity of bacterial...
Pneumonia is an infection of the lung alveoli caused by bacteria, viruses or fungi. It is one of the leading causes of morbidity and mortality worldwide, representing a clinical and economic burden and...
View ArticleScientists identify evolutionary gateway helping pneumonia bacteria become...
An evolutionary gateway which helps pneumonia cells become resistant to antibiotics has been discovered.
View ArticleMacaque trials offer hope in pneumonia vaccine development
A research team has successfully developed a novel pneumococcal vaccine by combining the team's proprietary mucosal vaccine technology with pneumococcal surface proteins that can cover a wide range of...
View ArticleMacaque trials offer hope in pneumonia vaccine development
A research team has successfully developed a novel pneumococcal vaccine by combining the team's proprietary mucosal vaccine technology with pneumococcal surface proteins that can cover a wide range of...
View ArticleToothbrushing tied to lower rates of pneumonia among hospitalized patients
Researchers have found an inexpensive tool that may help reduce rates of pneumonia for hospitalized patients -- and it comes with bristles on one end. A new study examined whether daily toothbrushing...
View Article
